The team at Memorial Sloan-Kettering Cancer Center (MSK) has reported the results of a clinical trial for the first time in this regard.
“This study demonstrates the power of nutrition — specifically a high-fiber plant-based diet — and opens up a better understanding of how it affects the microbiome and metabolism,” said MSK myeloma specialist Dr. Arvi Shah. can lead to improvements to build a stronger immune system.” , who presented these findings at the 2024 American Society of Hematology (ASH) Annual Meeting in San Diego, California.
“These findings further support how we as clinicians can empower patients, especially those with pre-existing conditions, to reduce cancer risk through dietary changes,” he added. With knowledge about reducing.
The study enrolled 20 participants who were at risk of developing multiple myeloma with a blood disorder and an elevated body mass index (BMI).
They received 12 weeks of a high-fiber, plant-based diet and 24 weeks of coaching. Two participants with progressive disease prior to the study showed significant improvement in the rate of progression of their disease.
Additionally, one year after enrollment, none of the participants had progressed to multiple myeloma.
During the study, participants were encouraged to eat as much as they wanted if it was whole plant-based foods such as fruits, vegetables, nuts, seeds, whole grains and beans.
With these dietary changes, there were significant improvements in quality of life, insulin resistance, gut microbiome health, and inflammation.
On average, participants lost eight percent of their body weight after 12 weeks.
These results were confirmed in a smoldering myeloma mouse model where 44% of mice fed a high-fiber diet did not develop myeloma compared to a standard diet where all mice developed myeloma.